These are definitely great boots (I have the quest 4D GTX brown/grey). I'm a multiday backpacker as well and these were the boots I chose. I went for the best boots I could get period, price not a factor and these have been the best boots I've ever had.
I have high arches though so I went with heat moldable SOLE inserts which also have the anti-bacterial built in to them. Best insoles I've ever tried (I've tried a lot) and at $50 they aren't cheap but well worth it. They come in difference thicknesses for personal preference. For hiking I use a thicker insole for more cushioning.
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